3352 Stathmin Antibody #3352

"上海博耀生物销售Stathmin Antibody #3352，CST原装品质，价格优惠，订购Stathmin Antibody #3352，详情请咨询销售人员！产品详

"上海博耀生物销售Stathmin Antibody #3352，CST原装品质，价格优惠，订购Stathmin Antibody #3352，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Stathmin Antibody #3352
货号：3352
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3352S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IHC-P	H M R Mk	Endogenous	19	Rabbit

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Stathmin Antibody detects endogenous levels of total stathmin protein. The antibody does not cross-react with related proteins such as SCG10, SCLIP and RB3.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser38 of human stathmin. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Stathmin is a ubiquitously expressed microtubule destabilizing phosphoprotein that is upregulated in a number of cancers. The amino terminus of the protein contains multiple phosphorylation sites and is involved in the promotion of tubulin filament depolymerization. Phosphorylation at these sites inactivates the protein and stabilizes microtubules. Ser16 phosphorylation by CaM kinases II and IV (1,2) increases during G2/M-phase and is involved in mitotic spindle regulation (3,4). Ser38 is a target for cdc2 kinase (5) and TNF-induced cell death gives rise to reactive oxygen intermediates leading to hyperphosphorylation of stathmin (6). EGF receptor activation of Rac and cdc42 also increases phosphorylation of stathmin on Ser16 and Ser38 (7). Other closely related family members are neuronally expressed and include SCG10, SCLIP, RB3 and its splice variants RB3' and RB3''. Stathmin and SCG10 have been shown to play roles in neuronal-like development in PC12 cells (8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab102548/Anti-CRTAC1 antibody
ab103117/Anti-C1RL antibody
Anti-FAM63AFAM63A蛋白抗体
ab101337/Anti-GPKOW antibody
ab103706/Anti-FBXL14 antibody
ab103822/Anti-CEACAM21 antibody
Anti-Insulin抗重组人胰岛素抗体
ab102816/Anti-GSTA3 antibody
ab10223/Anti-Cardiac Troponin T antibody
Anti-TNF alpha肿瘤坏死因子-α/TNFα抗体
Anti-FasL/CD178兔抗FasL抗体。
ab10237/Anti-cardiac Troponin I antibody
ab103682/Anti-DNA helicase HEL308 antibody
ab10400/Anti-CXCR1 antibody
ab103570/Anti-Caspase 6 antibody
Anti-TSHR促甲状腺素受体抗体"
本页产品地址：http://www.geilan.com/sell/show-3245089.html