3336 S5a/PSMD4 (D17E4) Rabbit mAb #3336

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"上海博耀生物销售S5a/PSMD4 (D17E4) Rabbit mAb #3336，CST原装品质，价格优惠，订购S5a/PSMD4 (D17E4) Rabbit mAb #3336，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：S5a/PSMD4 (D17E4) Rabbit mAb #3336
货号：3336
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
3336S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP	H M R Mk (Hm) (X) (Z) (B) (Dg) (Pg) (Hr)	Endogenous	50	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  Hm=Hamster  Mk=Mon key  X=Xenopus  Z=Zebrafish  B=Bovine  Dg=Dog  Pg=Pig  Hr=Horse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： S5a/PSMD4 (D17E4) Rabbit mAb recognizes endogenous levels of total S5a/PSMD4 protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human S5a/PSMD4 protein.
抗体背景：

S5a (PSMD4) is a subunit of the 19S regulatory proteasome complex functioning in ubiquitinated-protein targeting and degradation (1). S5a contains two polyubiquitin binding motifs (UIM) that bind multiubiquitin chains by hydrophobic interaction (2,3). In addition to ubiquitin, the UIM of S5a shows high affinity to a ubiquitin-like domain present in many proteins. S5a binds to these types of proteins directly and mediates their targeting to the proteasome for degradation (4,5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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