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3318 Cofilin (D59) Antibody #3318

会员指数: 企业认证:

价格:电议

所在地:上海

型号:3318

更新时间:2013-07-29

浏览次数:665

公司地址:

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产品简介

"上海博耀生物销售Cofilin (D59) Antibody #3318,CST原装品质,价格优惠,订购Cofilin (D59) Antibody #3318,详情请咨询销售人

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"上海博耀生物销售Cofilin (D59) Antibody #3318,CST原装品质,价格优惠,订购Cofilin (D59) Antibody #3318,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Cofilin (D59) Antibody #3318
货号:3318
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
3318S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W H M R Mk B Endogenous 19 Rabbit
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Cofilin (D59) Antibody detects endogenous levels of total cofilin protein.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp59 of human cofilin. Antibodies are purified by protein A and peptide affinity chromatography.  
抗体背景:

Cofilin and actin-depolymerization factor (ADF) are members of a family of essential conserved small actin-binding proteins that play pivotal roles in cytokinesis, endocytosis, embryonic development, stress response, and tissue regeneration (1). In response to stimuli, cofilin promotes the regeneration of actin filaments by severing preexisting filaments (2). The severing activity of cofilin is inhibited by LIMK or TESK phosphorylation at Ser3 of cofilin (3-5). Phosphorylation at Ser3 also regulates cofilin translocation from the nucleus to the cytoplasm (6).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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