3313 Phospho-Cofilin (Ser3) (77G2) Rabbit mAb #3313

"上海博耀生物销售Phospho-Cofilin (Ser3) (77G2) Rabbit mAb #3313，CST原装品质，价格优惠，订购Phospho-Cofilin (Ser3) (77G2

"上海博耀生物销售Phospho-Cofilin (Ser3) (77G2) Rabbit mAb #3313，CST原装品质，价格优惠，订购Phospho-Cofilin (Ser3) (77G2) Rabbit mAb #3313，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Cofilin (Ser3) (77G2) Rabbit mAb #3313
货号：3313
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
3313P	40 ul (4 western blots)	询价
3313S	100 ul (10 western blots)	询价
3313L	300 ul (30 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IF-IC	H M R Mk B	Endogenous	19	Rabbit IgG

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Cofilin (Ser3) (77G2) Rabbit mAb detects endogenous levels of cofilin only when phosphorylated at serine 3.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser3 of human cofilin.
抗体背景：

Cofilin and actin-depolymerization factor (ADF) are members of a family of essential conserved small actin-binding proteins that play pivotal roles in cytokinesis, endocytosis, embryonic development, stress response, and tissue regeneration (1). In response to stimuli, cofilin promotes the regeneration of actin filaments by severing preexisting filaments (2). The severing activity of cofilin is inhibited by LIMK or TESK phosphorylation at Ser3 of cofilin (3-5). Phosphorylation at Ser3 also regulates cofilin translocation from the nucleus to the cytoplasm (6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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