3312 Cofilin Antibody #3312

"上海博耀生物销售Cofilin Antibody #3312，CST原装品质，价格优惠，订购Cofilin Antibody #3312，详情请咨询销售人员！产品详细

"上海博耀生物销售Cofilin Antibody #3312，CST原装品质，价格优惠，订购Cofilin Antibody #3312，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Cofilin Antibody #3312
货号：3312
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3312S	100 ul (10 western blots)	询价
3312L	300 ul (30 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Hm Mk B (Pg)	Endogenous	19	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Hm=Hamster  Mk=Mon key  B=Bovine  Pg=Pig
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Cofilin Antibody detects endogenous levels of total cofilin protein. The antibody may also recognize cofilin 2, the muscle isoform.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser3 of human cofilin. Antibodies are purified by protein A.
抗体背景：

Cofilin and actin-depolymerization factor (ADF) are members of a family of essential conserved small actin-binding proteins that play pivotal roles in cytokinesis, endocytosis, embryonic development, stress response, and tissue regeneration (1). In response to stimuli, cofilin promotes the regeneration of actin filaments by severing preexisting filaments (2). The severing activity of cofilin is inhibited by LIMK or TESK phosphorylation at Ser3 of cofilin (3-5). Phosphorylation at Ser3 also regulates cofilin translocation from the nucleus to the cytoplasm (6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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