产品简介
"上海博耀生物销售VRK1 (1F6) Mouse mAb #3307,CST原装品质,价格优惠,订购VRK1 (1F6) Mouse mAb #3307,详情请咨询销售人员!
产品说明
"上海博耀生物销售
VRK1 (1F6) Mouse mAb #3307,CST原装品质,价格优惠,订购
VRK1 (1F6) Mouse mAb #3307,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:VRK1 (1F6) Mouse mAb #3307
货号:3307
品牌:CST(cell signaling)
抗体来源:Mouse
克隆类型:
Monoclonal
规格:
| No. |
Size |
Price |
| 3307S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Isotype |
| W |
H |
Endogenous |
48 |
Mouse IgG1 |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
VRK1 (1F6) Mouse mAb detects endogenous levels of total VRK1 protein.
来源及纯化方法:
Monoclonal antibody is produced by immunizing animals with recombinant fusion protein GST-full length human VRK1.
抗体背景:
The vaccinia-related kinase (VRK) proteins are a new group of Ser/Thr kinases in the human kinome. This mammalian kinase family comprises three members, VRK1, VRK2, and VRK3 (1-3). The VRK1 has autophosphorylation activity and phosphorylates several transcription factors, including p53 (4), ATF2 (5), and c-Jun (6). VRK2 is associated with the endoplasmic reticulum (7). VRK3 suppresses Erk activity through direct interaction and activation of the MAP kinase phosphatase VHR (8). Further functional and structural analysis of VRK proteins will elucidate important new aspects of cell regulation.
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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