3297 SPHK1 Antibody #3297

"上海博耀生物销售SPHK1 Antibody #3297，CST原装品质，价格优惠，订购SPHK1 Antibody #3297，详情请咨询销售人员！产品详细参数

"上海博耀生物销售SPHK1 Antibody #3297，CST原装品质，价格优惠，订购SPHK1 Antibody #3297，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：SPHK1 Antibody #3297
货号：3297
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3297S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Mk	Endogenous	45	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： SPHK1 Antibody detects endogenous levels of total SPHK1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human SPHK1. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Sphingosine kinases (SPHKs) catalyze the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Together with other sphingolipid metabolizing enzymes, SPHKs regulate the balance of the lipid mediators, ceramide, sphingosine, and S1P (1-4). Two distinct SPHK isoforms, SPHK1 and SPHK2, have been cloned and characterized (5,6). SPHK1 and SPHK2 are highly conserved and diversely expressed (7,8). The SPHKs are activated by G protein-coupled receptors, receptor tyrosine kinases, immunoglobulin receptors, cytokines, and other stimuli (9-12). The molecular mechanisms by which SPHK1 and SPHK2 are specifically regulated are complex and only partially understood.

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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