3296 PIP5K1C Antibody #3296

"上海博耀生物销售PIP5K1C Antibody #3296，CST原装品质，价格优惠，订购PIP5K1C Antibody #3296，详情请咨询销售人员！产品详细

"上海博耀生物销售PIP5K1C Antibody #3296，CST原装品质，价格优惠，订购PIP5K1C Antibody #3296，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：PIP5K1C Antibody #3296
货号：3296
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3296S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Mk	Endogenous	87, 90	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： PIP5K1C Antibody detects endogenous levels of total PIP5K1C protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues around Gly504 of human PIP5K1C. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Phosphatidylinositol-5-phosphate 4-kinases (PIP4K) synthesize phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P₂), a key precursor in phosphoinositide signaling that directly modulates the activity of signaling proteins and cellular processes. There are two subfamilies of PIP kinases, type I and II, that generate PtdIns(4,5)P₂ from distinct substrate pools. PIP4 type I kinases use PtdIns5P as a substrate, whereas PIP5 type II kinases use PtdIns4P (1,2). In mammalian cells, three isoforms of each PIP4K and PIP5K subfamily, encoded by distinct genes, have been characterized (3-7). All PIP kinases are stimulated by phosphatidic acid, extensively regulated by ARF and Rho GTPases, and inhibited by protein kinase A and PI-stimulated autophosphorylation (8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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