3290 Endoglin Antibody (Mouse Specific) #3290

"上海博耀生物销售Endoglin Antibody (Mouse Specific) #3290，CST原装品质，价格优惠，订购Endoglin Antibody (Mouse Specific)

"上海博耀生物销售Endoglin Antibody (Mouse Specific) #3290，CST原装品质，价格优惠，订购Endoglin Antibody (Mouse Specific) #3290，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Endoglin Antibody (Mouse Specific) #3290
货号：3290
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3290S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	M	Transfected Only	79, 81	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Endoglin Antibody (Mouse Specific) detects transfected levels of mouse endoglin protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro430 of mouse endoglin. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Endoglin (ENG, CD105) is an auxiliary receptor for the TGF-β receptor complex, functioning in related signaling pathways (1,2). Endoglin is a transmembrane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells. Upregulated endoglin expression has been reported during wound healing and tumor vascularization, and in inflammatory tissues and developing embryos (1-4). Mutations in endoglin have been found to be a causal factor of hereditary hemorrhagic telangiectasia (HHT), a disease characterized by malformation of vascular structure (5,6). The importance of this protein for normal and tumor vascular function makes it a good marker for endothelial cell proliferation as well as a potential therapeutic target in cancer (4-6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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