3285 FAK Antibody #3285

"上海博耀生物销售FAK Antibody #3285，CST原装品质，价格优惠，订购FAK Antibody #3285，详情请咨询销售人员！产品详细参数如下

"上海博耀生物销售FAK Antibody #3285，CST原装品质，价格优惠，订购FAK Antibody #3285，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：FAK Antibody #3285
货号：3285
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3285P	40 ul (4 western blots)	询价
3285S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP IHC-P	H M R Mk B Pg (C)	Endogenous	125	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  C=Chicken  B=Bovine  Pg=Pig
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： FAK Antibody detects endogenous levels of FAK protein. This antibody does not cross-react with other proteins.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding amino acid 710 of human FAK. Antibodies are purified by protein A and peptide affinity chramotography.
抗体背景：

Focal adhesion kinase (FAK) is a widely expressed cytoplasmic protein tyrosine kinase involved in integrin-mediated signal transduction. It plays an important role in the control of several biological processes, including cell spreading, migration, and survival (1). Activation of FAK by integrin clustering leads to autophosphorylation at Tyr397, which is a binding site for the Src family kinases PI3K and PLCγ (2-5). Recruitment of Src family kinases results in the phosphorylation of Tyr407, Tyr576, and Tyr577 in the catalytic domain, and Tyr871 and Tyr925 in the carboxy-terminal region of FAK (6,7).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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