3277 HAUSP Antibody #3277

"上海博耀生物销售HAUSP Antibody #3277，CST原装品质，价格优惠，订购HAUSP Antibody #3277，详情请咨询销售人员！产品详细参数

"上海博耀生物销售HAUSP Antibody #3277，CST原装品质，价格优惠，订购HAUSP Antibody #3277，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：HAUSP Antibody #3277
货号：3277
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3277S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R	Endogenous	135	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： HAUSP Antibody detects endogenous levels of total HAUSP protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp438 of human HAUSP. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action (1,2). Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD and JAMM enzymes. Herpesvirus-associated ubiquitin-specific protease (HAUSP, USP7) is an important deubiquitinase belonging to USP subfamily. A key HAUSP function is to bind and deubiquitinate the p53 transcription factor and an associated regulator protein Mdm2, thereby stabilizing both proteins (3,4). In addition to regulating essential components of the p53 pathway, HAUSP also modifies other ubiquitinylated proteins such as members of the FoxO family of forkhead transcription factors and the mitotic stress checkpoint protein CHFR (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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