3274 GβL (86B8) Rabbit mAb #3274

"上海博耀生物销售GβL (86B8) Rabbit mAb #3274，CST原装品质，价格优惠，订购GβL (86B8) Rabbit mAb #3274，详情请咨询销售人

"上海博耀生物销售GβL (86B8) Rabbit mAb #3274，CST原装品质，价格优惠，订购GβL (86B8) Rabbit mAb #3274，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：GβL (86B8) Rabbit mAb #3274
货号：3274
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： GβL
规格：

No.	Size	Price
3274P	40 ul (4 western blots)	询价
3274S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP	H M R Mk	Endogenous	37	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： GβL (86B8) Rabbit mAb detects endogenous levels of total GβL protein.
来源及纯化方法： GβL (86B8) Rabbit mAb is produced by immunizing rabbits with a synthetic peptide corresponding to residues surrounding Gln210 of human GβL.
抗体背景：

Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian Target of Rapamycin (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals (1). mTOR is a large protein kinase with two different complexes. One complex contains mTOR, GβL, and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GβL, and rictor (1). GβL associates with the kinase domain of mTOR and stimulates mTOR kinase activity (2). A reduction in GβL expression has been shown to decrease in vivo phosphorylation of S6K1 (2).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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