3256 CLK3 Antibody #3256

"上海博耀生物销售CLK3 Antibody #3256，CST原装品质，价格优惠，订购CLK3 Antibody #3256，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售CLK3 Antibody #3256，CST原装品质，价格优惠，订购CLK3 Antibody #3256，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：CLK3 Antibody #3256
货号：3256
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3256S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IF-IC	H M R Mk	Endogenous	59, 17	Rabbit

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： CLK3 Antibody detects endogenous levels of full-length and truncated forms of CLK3 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His51 of CLK3. Antibodies were purified by protein A and peptide affinity chromatography.
抗体背景：

The cdc2-like kinase (CLK) family contains at least four highly conserved isoforms: CLK1, CLK2, CLK3 and CLK4 (1,2). CLKs are dual specificity kinases that autophosphorylate on serine, threonine and tyrosine residues and phosphorylate exogenous substrates on serine and threonine residues (2). CLK family members exist as both a full-length catalytically active form and an alternatively-spliced, inactive truncated form (1). A family of highly phosphorylated proteins, called serine and arginine rich (SR) proteins, are phosphorylated by CLKs (3-5). SR proteins are splicing factors that regulate the assembly of the spliceosome, a macromolecular complex where RNA splicing occurs in the nucleus. They are also involved in the selection of splice sites. Thus, CLKs may play important roles in regulating RNA splicing.

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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