3254 DR3 Antibody #3254

"上海博耀生物销售DR3 Antibody #3254，CST原装品质，价格优惠，订购DR3 Antibody #3254，详情请咨询销售人员！产品详细参数如下

"上海博耀生物销售DR3 Antibody #3254，CST原装品质，价格优惠，订购DR3 Antibody #3254，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：DR3 Antibody #3254
货号：3254
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： DR3
规格：

No.	Size	Price
3254S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H	Endogenous	48	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： DR3 Antibody detects endogenous levels of human DR3. It is not expected to cross-react with other TNF receptor family members.
来源及纯化方法： DR3 Antibody is produced by immunizing rabbits with a synthetic peptide corresponding to residues within the intracellular domain of human DR3. Antibodies were purified by protein A and peptide affinity chromatography.
抗体背景：

The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1,2). The receptors are activated by a family of cytokines that include TNF, FasL, and TRAIL. They are characterized by a highly conserved extracellular region containing cysteine-rich repeats and a conserved intracellular region of about 80 amino acids termed the death domain (DD). The DD is important for transducing the death signal by recruiting other DD containing adaptor proteins (FADD, TRADD, RIP) to the death-inducing signaling complex (DISC), resulting in activation of caspases.

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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