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3253 Flotillin-1 Antibody #3253

会员指数: 企业认证:

价格:电议

所在地:上海

型号:3253

更新时间:2013-07-29

浏览次数:751

公司地址:

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产品简介

"上海博耀生物销售Flotillin-1 Antibody #3253,CST原装品质,价格优惠,订购Flotillin-1 Antibody #3253,详情请咨询销售人员!

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"上海博耀生物销售Flotillin-1 Antibody #3253,CST原装品质,价格优惠,订购Flotillin-1 Antibody #3253,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Flotillin-1 Antibody #3253
货号:3253
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
3253S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W H M R Mk Endogenous 49 Rabbit
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Flotillin-1 Antibody detects endogenous levels of total flotillin-1 protein.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding residue surrounding Ile368 of human flotillin-1. Antibodies are purified by peptide affinity chromatography.
抗体背景:

Flotillins belong to a family of lipid raft-associated integral membrane proteins that carry a evolutionarily conserved domain called the prohibitin homology domain (PHB) (1). Flotillin members are ubiquitously expressed and located to non-caveolar microdomains (lipid rafts) on the cell plasma membrane where they support signal transduction and regulate lipid raft motility and localization (2-5). Two flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found at compartments of the endocytic and autophagosomal pathways, such as recycling/late endosomes, the Golgi complex, as well as the nucleus (6,7). Flotillin-2 is mainly localized to the plasma membrane and is prevalent in cell-cell contact sites. However, overexpressed flotillin-2 has also been found in the late endosome (4,8,9). Both flotillin-1 and flotillin-2 are commonly used as lipid raft associated markers.

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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