产品简介
"上海博耀生物销售Flotillin-1 Antibody #3253,CST原装品质,价格优惠,订购Flotillin-1 Antibody #3253,详情请咨询销售人员!
产品说明
"上海博耀生物销售
Flotillin-1 Antibody #3253,CST原装品质,价格优惠,订购
Flotillin-1 Antibody #3253,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:Flotillin-1 Antibody #3253
货号:3253
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 3253S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
H M R Mk |
Endogenous |
49 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Mk=Mon
key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
Flotillin-1 Antibody detects endogenous levels of total flotillin-1 protein.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding residue surrounding Ile368 of human flotillin-1. Antibodies are purified by peptide affinity chromatography.
抗体背景:
Flotillins belong to a family of lipid raft-associated integral membrane proteins that carry a evolutionarily conserved domain called the prohibitin homology domain (PHB) (1). Flotillin members are ubiquitously expressed and located to non-caveolar microdomains (lipid rafts) on the cell plasma membrane where they support signal transduction and regulate lipid raft motility and localization (2-5). Two flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found at compartments of the endocytic and autophagosomal pathways, such as recycling/late endosomes, the Golgi complex, as well as the nucleus (6,7). Flotillin-2 is mainly localized to the plasma membrane and is prevalent in cell-cell contact sites. However, overexpressed flotillin-2 has also been found in the late endosome (4,8,9). Both flotillin-1 and flotillin-2 are commonly used as lipid raft associated markers.
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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