3243 LAMP1 (C54H11) Rabbit mAb #3243

"上海博耀生物销售LAMP1 (C54H11) Rabbit mAb #3243，CST原装品质，价格优惠，订购LAMP1 (C54H11) Rabbit mAb #3243，详情请咨询

"上海博耀生物销售LAMP1 (C54H11) Rabbit mAb #3243，CST原装品质，价格优惠，订购LAMP1 (C54H11) Rabbit mAb #3243，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：LAMP1 (C54H11) Rabbit mAb #3243
货号：3243
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
3243S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H M Mk	Endogenous	42 (non-glycosylated), 90-120 (glycosylated)	Rabbit IgG

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： LAMP1 (C54H11) Rabbit mAb detects endogenous levels of total LAMP1 protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide surrounding Ser140 of human LAMP1.
抗体背景：

Lysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins (1,2). Both are transmembrane proteins and are heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis (3). The carboxy terminus of LAMP1 is exposed to the cytoplasm and contains a tyrosine sorting motif that targets LAMP to lysosomal membranes (4). LAMP1 and LAMP2 are 37% homologous in their protein sequences. Both LAMP1 and LAMP2 are involved in regulating lysosomal motility during lysosome-phagosome fusion and cholesterol trafficking (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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