3235 SKAR Antibody #3235

"上海博耀生物销售SKAR Antibody #3235，CST原装品质，价格优惠，订购SKAR Antibody #3235，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售SKAR Antibody #3235，CST原装品质，价格优惠，订购SKAR Antibody #3235，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：SKAR Antibody #3235
货号：3235
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3235S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Mk	Endogenous	46	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： SKAR Antibody detects endogenous levels of total SKAR protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human SKAR alpha. Antibodies are purified using protein A and peptide affinity chromotography.
抗体背景：

p70 S6 kinase is a mitogen activated Ser/Thr protein kinase downstream of phosphoinositide-3 kinase (PI3K) and the target of rapamycin, FRAP/mTOR. p70 S6 kinase is required for cell growth and cell cycle progression (1,2). SKAR is a recently discovered substrate of S6K1. SKAR exists in two isoforms, α and β, the latter having a 29 amino acid truncation. Phosphorylation of SKAR is mitogen-induced and sensitive to rapamycin. Reduction in SKAR protein levels results in decreased cell size, further implicating SKAR in cell growth control (3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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