3221 Phospho-Ret (Tyr905) Antibody #3221

"上海博耀生物销售Phospho-Ret (Tyr905) Antibody #3221，CST原装品质，价格优惠，订购Phospho-Ret (Tyr905) Antibody #3221，详

"上海博耀生物销售Phospho-Ret (Tyr905) Antibody #3221，CST原装品质，价格优惠，订购Phospho-Ret (Tyr905) Antibody #3221，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Ret (Tyr905) Antibody #3221
货号：3221
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3221S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H Dm	Endogenous	175	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  Dm=D. melanogaster
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Ret (Tyr905) Antibody detects endogenous levels of Ret only when phosphorylated at tyrosine 905. This antibody may cross-react with other activated receptor tyrosine kinases.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr905 of human Ret. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The Ret proto-oncogene (c-Ret) is a receptor tyrosine kinase that functions as a multicompetent receptor complex in conjunction with other membrane-bound, ligand-binding GDNF family receptors (1). Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin, and artemin (2-4). Research studies have shown that alterations in the corresponding RET gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma, and a congenital developmental disorder known as Hirschsprung’s disease (1,3). The Tyr905 residue located in the Ret kinase domain plays a crucial role in Ret catalytic and biological activity. Substitution of Phe for Tyr at position 905 dramatically inhibits Ret autophosphorylation activity (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-RGS2G蛋白信号转导调节因子2抗体
Anti-CGP-39/YKL-40软骨糖蛋白39抗体
ab103078/Anti-FANCA antibody
ab102576/Anti-FUBP3 antibody
Anti-ER α雌激素受体α抗体
ab102934/Anti-CD7 antibody
Anti-PMP22外周髓鞘蛋白-22抗体
Anti-HSP60热休克蛋白-60抗体
Anti-CD147/TCSF/Emmprin细胞外基质金属蛋白酶诱导因子抗体
Anti-TGF Beta R1/TGFBR1转移生长因子β受体1抗体（TGF-βRⅠ，TGFβRⅠ）
Anti-Nanog胚胎干细胞关键蛋白抗体
Anti-DFF-40beta/CAD/CPANCaspase 激活的脱氧核糖核酸酶抗体
ab102829/Anti-C20orf70 antibody
Anti-NAP1L1核小体组装蛋白1抗体
Anti-Melanoma HMB45/Melanoma/Melan-A/MART-1黑色素瘤相关抗原/黑色素-A抗体
Anti-GLP-1 (7-36)胰高血糖素样肽-1抗体"
本页产品地址：http://www.geilan.com/sell/show-3244952.html