3211 Phospho-Etk (Tyr40) Antibody #3211

"上海博耀生物销售Phospho-Etk (Tyr40) Antibody #3211，CST原装品质，价格优惠，订购Phospho-Etk (Tyr40) Antibody #3211，详情

"上海博耀生物销售Phospho-Etk (Tyr40) Antibody #3211，CST原装品质，价格优惠，订购Phospho-Etk (Tyr40) Antibody #3211，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Etk (Tyr40) Antibody #3211
货号：3211
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3211S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H	Endogenous	76	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Etk (Tyr40) Antibody detects endogenous levels of Etk only when phosphorylated at Tyr40. This antibody may cross react with activated EGF Receptor. This antibody may cross react with other family members including ITK and BTK when overexpressed.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr40 of human Etk. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Etk, also known as BMX, is a member of the Bruton's tyrosine kinase (Btk) family (1). It is expressed in a variety of hematopoietic, epithelial and endothelial cells. Etk, like other Btk family members, contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. It participates in multiple signal transduction pathways (2). Phosphorylation of Tyr566 by Src kinase is required for activation of Etk in vivo (3). In endothelial and epithelial cells, Etk is regulated by FAK through phosphorylation at Tyr40 (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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