3192 PERK (C33E10) Rabbit mAb #3192

"上海博耀生物销售PERK (C33E10) Rabbit mAb #3192，CST原装品质，价格优惠，订购PERK (C33E10) Rabbit mAb #3192，详情请咨询销

"上海博耀生物销售PERK (C33E10) Rabbit mAb #3192，CST原装品质，价格优惠，订购PERK (C33E10) Rabbit mAb #3192，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：PERK (C33E10) Rabbit mAb #3192
货号：3192
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
3192S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H M R Mk	Endogenous	140	Rabbit IgG

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： PERK (C33E10) Rabbit mAb detects endogenous levels of total PERK protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human PERK.
抗体背景：

Protein kinase-like endoplasmic reticulum kinase (PERK) is an eIF2α kinase and transmembrane protein resident in the endoplasmic reticulum (ER) membrane that couples ER stress signals to translation inhibition (1-3). ER stress increases the activity of PERK, which then phosphorylates eIF2α to promote reduced translation. Research studies have demonstrated that PERK-deficient mice have defects in pancreatic β cells several weeks after birth, suggesting a role for PERK-mediated translational control in protecting secretory cells from ER stress (4). PERK activation during ER stress correlates with autophosphorylation of its cytoplasmic kinase domain (1-3). Phosphorylation of PERK at Thr980 serves as a marker for its activation status.

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-Gliomedin/COLM神经胶质蛋白(肝癌相关基因2)抗体
Anti-VAT1L/KIAA1576突触小泡膜蛋白同源样蛋白1抗体
ab100951/Anti-Chicken Erythrocyte Linker Histone H5 antibody
Anti-AD7C-NTP神经丝蛋白抗体
ab102544/Anti-E2 230K antibody
Anti-GAPDH3-磷酸甘油醛脱氢酶（兔来源免疫组化用抗体）
ab103547/Anti-CYP2C8 antibody
ab102650/Anti-GALNT2 antibody
Anti-TLR4/CD284Toll样受体4抗体
ab103737/Anti-APOBEC4 antibody
Anti-ASTN2星形肌动蛋白抗体
ab100804/Anti-DAP3 antibody
Anti-TIGARTIGAR蛋白抗体
ab10407/Anti-Eph receptor B1 antibody
ab103222/Anti-BPY2 antibody
Anti-VAP1血管粘附蛋白1抗体"
本页产品地址：http://www.geilan.com/sell/show-3244925.html