3187 NQO1 (A180) Mouse mAb #3187

"上海博耀生物销售NQO1 (A180) Mouse mAb #3187，CST原装品质，价格优惠，订购NQO1 (A180) Mouse mAb #3187，详情请咨询销售人员

"上海博耀生物销售NQO1 (A180) Mouse mAb #3187，CST原装品质，价格优惠，订购NQO1 (A180) Mouse mAb #3187，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：NQO1 (A180) Mouse mAb #3187
货号：3187
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： NQO1
规格：

No.	Size	Price
3187S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IHC-P IF-IC	H	Endogenous	29	Mouse IgG1

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： NQO1 (A180) Mouse mAb detects endogenous levels of total NQO1 protein.
来源及纯化方法： NQO1 (A180) Mouse mAb is produced by immunizing mice with purified recombinant human NQO1.
抗体背景：

NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoprotein that catalyzes the two-electron reduction of quinones and their derivatives (1,2). This enzyme protects cells against redox cycling and oxidative stress (1,3). The expression of NQO1 is increased in liver, colon and breast tumors and non-small cell lung cancer (NSCLC) compared with the normal tissues (1,2). Moreover, expression levels are also elevated in developing tumors, suggesting a role for NQ01 in the prevention of tumor development (1). Studies on NQO1 knockout mice suggest that the lack of NQO1 enzymatic activity changes intracellular redox states resulting in a reduction in apoptosis, which in turns leads to myeloid hyperplasia of bone marrow (2).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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