3180 Fatty Acid Synthase (C20G5) Rabbit mAb #3180

"上海博耀生物销售Fatty Acid Synthase (C20G5) Rabbit mAb #3180，CST原装品质，价格优惠，订购Fatty Acid Synthase (C20G5) Ra

"上海博耀生物销售Fatty Acid Synthase (C20G5) Rabbit mAb #3180，CST原装品质，价格优惠，订购Fatty Acid Synthase (C20G5) Rabbit mAb #3180，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Fatty Acid Synthase (C20G5) Rabbit mAb #3180
货号：3180
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Fatty
规格：

No.	Size	Price
3180S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P IHC-F IF-IC	H M R (B)	Endogenous	273	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IHC-F=Immunohistochemistry (Frozen)  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat  B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Fatty Acid Synthase (C20G5) Rabbit mAb detects endogenous levels of total fatty acid synthase protein.
来源及纯化方法： Fatty Acid Synthase (C20G5) Rabbit mAb is produced by immunizing rabbits with a synthetic peptide around Gly46 corresponding to the sequence of human fatty acid synthase.
抗体背景：

Fatty acid synthase (FASN) catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA. FASN is active as a homodimer with seven different catalytic activities and produces lipids in the liver for export to metabolically active tissues or storage in adipose tissue. In most other human tissues, FASN is minimally expressed since they rely on circulating fatty acids for new structural lipid synthesis (1).Recently, increased expression of FASN has emerged as a phenotype common to most human carcinomas. In breast cancer, immunohistochemical staining showed that the levels of FASN are directly related to the size of breast tumors (2). Studies also showed that FASN is highly expressed in lung and prostate cancers and that FASN expression is an indicator of poor prognosis in breast and prostate cancer (3-5). Furthermore, inhibition of FASN is selectively cytotoxic to human cancer cells (5). Thus, increased interest has focused on FASN as a potential target for the diagnosis and treatment of cancer as well as metabolic syndrome (6,7).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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