3165 Zap-70 (D1C10E) Rabbit mAb #3165

"上海博耀生物销售Zap-70 (D1C10E) Rabbit mAb #3165，CST原装品质，价格优惠，订购Zap-70 (D1C10E) Rabbit mAb #3165，详情请咨

"上海博耀生物销售Zap-70 (D1C10E) Rabbit mAb #3165，CST原装品质，价格优惠，订购Zap-70 (D1C10E) Rabbit mAb #3165，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Zap-70 (D1C10E) Rabbit mAb #3165
货号：3165
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
3165P	40 ul (8 western blots)	询价
3165S	100 ul (20 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IF-F F	H M	Endogenous	70	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IF-F=Immunofluorescence (Frozen)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Zap-70 (D1C10E) XP^® Rabbit mAb detects endogenous levels of total Zap-70. This antibody does not cross-react with other related proteins.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding the amino terminus of human Zap-70.
抗体背景：

The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement (1). Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck (2-6). Tyrosine phosphorylation correlates with increased Zap-70 kinase activity and downstream signaling events. Expression of Zap-70 is correlated with disease progression and survival in patients with chronic lymphocytic leukemia (7,8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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