3143 FoxA2/HNF3β Antibody #3143

"上海博耀生物销售FoxA2/HNF3β Antibody #3143，CST原装品质，价格优惠，订购FoxA2/HNF3β Antibody #3143，详情请咨询销售人员

"上海博耀生物销售FoxA2/HNF3β Antibody #3143，CST原装品质，价格优惠，订购FoxA2/HNF3β Antibody #3143，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：FoxA2/HNF3β Antibody #3143
货号：3143
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3143S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP IF-IC	H (M) (R)	Endogenous	50	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： FoxA2/HNF3β Antibody detects endogenous levels of total FoxA2/HNF3β protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to a sequence of human FoxA2/HNF3β. Antibodies are purified by Protein A and peptide affinity chromatography.
抗体背景：

Forkhead box protein A2 (FoxA2, also known as hepatocyte nuclear factor 3β or HNF3β) is a transcription factor that plays an important role in hepatocyte function (1). FoxA2/HNF3β is required for the activation of hepatic gluconeogenic gene expression during fasting (1). Together with the PGC-1β coactivator, FoxA2/HNF3β stimulates the expression of genes involved in fatty acid β-oxidation and therefore increases fatty acid metabolism (2). FoxA2/HNF3β, along with PGC-1β, also activates the expression of microsomal triacylglycerol transfer protein (MTP) and promotes VLDL secretion (2). In addition to its roles in metabolic syndromes, FoxA2/HNF3β is essential for development of the endoderm and midline structures in mouse embryos (3-5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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