3142 Ezrin/Radixin/Moesin Antibody #3142

"上海博耀生物销售Ezrin/Radixin/Moesin Antibody #3142，CST原装品质，价格优惠，订购Ezrin/Radixin/Moesin Antibody #3142，详

"上海博耀生物销售Ezrin/Radixin/Moesin Antibody #3142，CST原装品质，价格优惠，订购Ezrin/Radixin/Moesin Antibody #3142，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Ezrin/Radixin/Moesin Antibody #3142
货号：3142
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3142P	40 ul (4 western blots)	询价
3142S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IHC-P	H M R Mk B (X)	Endogenous	75 Moesin. 80 Ezrin and Radixin.	Rabbit

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  X=Xenopus  B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Ezrin/Radixin/Moesin Antibody detects endogenous levels of ezrin, radixin and moesin. The antibody does not cross-react with related proteins such as merlin or band 4.1.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the residues surrounding Thr567 of human ezrin. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The ezrin, radixin, and moesin (ERM) proteins function as linkers between the plasma membrane and the actin cytoskeleton and are involved in cell adhesion, membrane ruffling, and microvilli formation (1). ERM proteins undergo intra or intermolecular interaction between their amino- and carboxy-terminal domains, existing as inactive cytosolic monomers or dimers (2). Phosphorylation at a carboxy-terminal threonine residue (Thr567 of ezrin, Thr564 of radixin, Thr558 of moesin) disrupts the amino- and carboxy-terminal association and may play a key role in regulating ERM protein conformation and function (3,4). Phosphorylation at Thr567 of ezrin is required for cytoskeletal rearrangements and oncogene-induced transformation (5). Ezrin is also phosphorylated at tyrosine residues upon growth factor stimulation. Phosphorylation of Tyr353 of ezrin transmits a survival signal during epithelial differentiation (6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab104000/Anti-C9orf78 antibody
Anti-DBH多巴胺β羟化酶抗体
ab103682/Anti-DNA helicase HEL308 antibody
ab101450/Anti-CD2 antibody
ab103084/Anti-ARL6IP2 antibody
ab100905/Anti-GDAP1 antibody
Anti-CCK8胆囊收缩素8抗体
Anti-PKA/PKAcat/PKACB蛋白激酶A抗体
Anti-procollagen type IIAⅡ型胶原α1抗体
Anti-TIMP-1(NT)金属蛋白酶组织抑制因子-1抗体（N端）
ab103483/Anti-C21orf128 antibody
ab103552/Anti-CD44 antibody
ab102729/Anti-c21 orf63 antibody
Anti-APOA1载脂蛋白A1抗体
ab103655/Anti-CCDC94 antibody
Anti-Annexin V重组膜粘连蛋白5抗体"
本页产品地址：http://www.geilan.com/sell/show-3244875.html