3138 Phospho-Ack1 (Tyr284) Antibody #3138

"上海博耀生物销售Phospho-Ack1 (Tyr284) Antibody #3138，CST原装品质，价格优惠，订购Phospho-Ack1 (Tyr284) Antibody #3138，

"上海博耀生物销售Phospho-Ack1 (Tyr284) Antibody #3138，CST原装品质，价格优惠，订购Phospho-Ack1 (Tyr284) Antibody #3138，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Ack1 (Tyr284) Antibody #3138
货号：3138
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3138S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H (M) (R)	Transfected Only	135	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Ack1 (Tyr284) Antibody detects transfected levels of Ack1 only when phosphorylated at Tyr284.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr284 of human Ack1. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Ack1 and Ack2 (activated cdc42-associated kinase 1 and 2) are non-receptor tyrosine kinases that consist of a tyrosine kinase core, an SH3 domain, a cdc42/Rac-binding (CRIB) domain, a Ralt homology region and a proline-rich region (1,2). Ack1 and 2 are the only two tyrosine kinases known to interact with cdc42. Both Acks are activated by growth factors including EGF and PDGF, as well as by activated integrins through cell adhesion, and may serve to link receptor tyrosine kinase or G protein-coupled receptor signaling with cdc42. Acks may regulate cell growth, morphology and motility (3,4). Recent findings indicate that Ack1 may play a role in prostate tumorigenesis, making it a potential drug target for this type of cancer (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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