产品简介
"上海博耀生物销售CDK6 (DCS83) Mouse mAb #3136,CST原装品质,价格优惠,订购CDK6 (DCS83) Mouse mAb #3136,详情请咨询销售人
产品说明
"上海博耀生物销售
CDK6 (DCS83) Mouse mAb #3136,CST原装品质,价格优惠,订购
CDK6 (DCS83) Mouse mAb #3136,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:CDK6 (DCS83) Mouse mAb #3136
货号:3136
品牌:CST(cell signaling)
抗体来源:Mouse
克隆类型:
Monoclonal
规格:
| No. |
Size |
Price |
| 3136P |
40 ul (8 western blots) |
询价 |
| 3136S |
100 ul (20 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Isotype |
| W |
H M R |
Endogenous |
36 |
Mouse IgG1 |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
CDK6 (DCS83) Mouse mAb detects endogenous levels of total CDK6 protein.
来源及纯化方法:
Monoclonal antibody is produced by immunizing animals with recombinant human CDK6 corresponding to amino acids 30-65.
抗体背景:
The cyclin-dependent kinases form complexes with their cyclin partners and with CDK inhibitors. CDK6 and CDK4 associate with the D-type cyclins and target the retinoblastoma protein, allowing passage through the G1/S phase restriction point (1). CDK6/cyclin D complexes are sequestered in their inactive form through binding to one of the INK4 CDK inhibitor family members (2,3). Unlike the INK4 family of cdk inhibitors, the CDK inhibitor p21 Waf1/Cip1 may enhance the association of CDK4 and CDK6 with their cyclin D partners (4).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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