3108 Phospho-Smad2 (Ser465/467) (138D4) Rabbit mAb #3108

"上海博耀生物销售Phospho-Smad2 (Ser465/467) (138D4) Rabbit mAb #3108，CST原装品质，价格优惠，订购Phospho-Smad2 (Ser465/4

"上海博耀生物销售Phospho-Smad2 (Ser465/467) (138D4) Rabbit mAb #3108，CST原装品质，价格优惠，订购Phospho-Smad2 (Ser465/467) (138D4) Rabbit mAb #3108，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Smad2 (Ser465/467) (138D4) Rabbit mAb #3108
货号：3108
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
3108P	40 ul (4 western blots)	询价
3108S	100 ul (10 western blots)	询价
3108L	300 ul (30 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H M R Mi	Endogenous	60	Rabbit IgG

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mi=Mink
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Smad2 (Ser465/467) (138D4) Rabbit mAb detects endogenous levels of Smad2 only when dually phosphorylated at serines 465 and 467, and may detect Smad3 phosphorylated at the equivalent sites. This antibody does not cross-react with other Smad-related proteins.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser465/467 of human Smad2.
抗体背景：

Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-β signals from the cell surface into the nucleus. Three distinct classes of Smads have been defined: the receptor-regulated Smads (R-Smads), which include Smad1, 2, 3, 5, and 8; the common-mediator Smad (co-Smad), Smad4; and the antagonistic or inhibitory Smads (I-Smads), Smad6 and 7 (1-5). Activated type I receptors associate with specific R-Smads and phosphorylate them on a conserved carboxy terminal SSXS motif. The phosphorylated R-Smad dissociates from the receptor and forms a heteromeric complex with the co-Smad (Smad4), allowing translocation of the complex to the nucleus. Once in the nucleus, Smads can target a variety of DNA binding proteins to regulate transcriptional responses (6-8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-GLUT2葡萄糖转运蛋白2抗体
Anti-Caspase-9白介素1-β转化酶样凋亡蛋白酶6抗体
ab101532/Anti-CDX2 antibody
ab10041/Anti-Fas Ligand antibody
ab1011/Anti-Bovine Papilloma Virus E2 antibody
ab101685/Anti-CD44 antibody
ab103193/Anti-ABCF3 antibody
Anti-Lysozyme溶菌酶抗体
ab103180/Anti-CCDC47 antibody
Anti-albumin/AFM人血清白蛋白抗体
ab101533/Anti-CD43 antibody
ab100873/Anti-DDX5 antibody
Anti-CD4CD4抗体
ab101830/Anti-CST11 antibody
ab104170/Anti-ERp19 antibody
ab103039/Anti-EHBP1 antibody"
本页产品地址：http://www.geilan.com/sell/show-3244851.html