3101 Phospho-Smad2 (Ser465/467) Antibody #3101

"上海博耀生物销售Phospho-Smad2 (Ser465/467) Antibody #3101，CST原装品质，价格优惠，订购Phospho-Smad2 (Ser465/467) Antibo

"上海博耀生物销售Phospho-Smad2 (Ser465/467) Antibody #3101，CST原装品质，价格优惠，订购Phospho-Smad2 (Ser465/467) Antibody #3101，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Smad2 (Ser465/467) Antibody #3101
货号：3101
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3101S	100 ul (10 western blots)	询价
3101L	300 ul (30 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R (C) (X) (Z)	Endogenous	60	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  C=Chicken  X=Xenopus  Z=Zebrafish
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Smad2 (Ser465/467) Antibody detects endogenous levels of Smad2 only when dually phosphorylated at Ser465 and Ser467, and may detect phosphorylated Smad3 at its equivalent site. This antibody does not cross-react with other Smad-related proteins.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser465/467 of human Smad2. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-β signals from the cell surface into the nucleus. Three distinct classes of Smads have been defined: the receptor-regulated Smads (R-Smads), which include Smad1, 2, 3, 5, and 8; the common-mediator Smad (co-Smad), Smad4; and the antagonistic or inhibitory Smads (I-Smads), Smad6 and 7 (1-5). Activated type I receptors associate with specific R-Smads and phosphorylate them on a conserved carboxy terminal SSXS motif. The phosphorylated R-Smad dissociates from the receptor and forms a heteromeric complex with the co-Smad (Smad4), allowing translocation of the complex to the nucleus. Once in the nucleus, Smads can target a variety of DNA binding proteins to regulate transcriptional responses (6-8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-Cyclooxygenase 1/COX1前列腺素氧化环化酶1抗体
ab100859/Anti-ABCA6 antibody
Anti-HAPLN2透明质酸及粘蛋白2抗体
ab101764/Anti-DOC2B antibody
ab103569/Anti-COPZ2 antibody
Anti-phospho-Tau protein(Ser519)磷酸化微管相关蛋白抗体
ab101996/Anti-C3IP1 antibody
Anti-HER4/ErbB4HER4抗体
ab100802/Anti-FAM82A2 antibody
Anti-Nurr1核受体相关因子-1抗体
ab104186/Anti-C11orf16 antibody
ab100807/Anti-CPSF2 antibody
ab101071/Anti-Cre recombinase antibody
Anti-Nurr1核受体相关因子-1抗体
Anti-CD20CD20抗体
Anti-TIMP-2金属蛋白酶组织抑制因子-2抗体"
本页产品地址：http://www.geilan.com/sell/show-3244846.html