3059 HSPB8/HSP22 Antibody #3059

"上海博耀生物销售HSPB8/HSP22 Antibody #3059，CST原装品质，价格优惠，订购HSPB8/HSP22 Antibody #3059，详情请咨询销售人员！

"上海博耀生物销售HSPB8/HSP22 Antibody #3059，CST原装品质，价格优惠，订购HSPB8/HSP22 Antibody #3059，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：HSPB8/HSP22 Antibody #3059
货号：3059
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3059S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Mk	Endogenous	22	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： HSPB8/HSP22 Antibody detects endogenous levels of total HSPB8/HSP22 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human HSPB8/HSP22. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

HSPB8 (HSP22) is a member of the small heat shock protein superfamily and the human protein is most closely related to HSP27. Similar to most other small HSPs (sHSPs), HSPB8 is predominantly transcribed in skeletal muscle and heart (1). In a two hybrid screen, HSPB8 interacted preferentially with a triple aspartate form of HSP27 which mimics HSP27 phosphorylated at Ser15, Ser78, and Ser82, as compared to wild-type HSP27 (2). HSPB8 has two binding domains (N- and C-terminal) that are specific for different binding partners, and has the ability to bind to itself and other sHSPs such as HSPB7 and HSPB2 (3). The chaperone-like activity is of great importance to the function of HSP22 in various processes including proliferation, apoptosis and macroautophagy (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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