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3013 TBK1/NAK Antibody #3013

会员指数: 企业认证:

价格:电议

所在地:上海

型号:3013

更新时间:2013-07-29

浏览次数:769

公司地址:

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产品简介

"上海博耀生物销售TBK1/NAK Antibody #3013,CST原装品质,价格优惠,订购TBK1/NAK Antibody #3013,详情请咨询销售人员!产品详

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"上海博耀生物销售TBK1/NAK Antibody #3013,CST原装品质,价格优惠,订购TBK1/NAK Antibody #3013,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:TBK1/NAK Antibody #3013
货号:3013
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
3013S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W IP H M R Mk Endogenous 84 Rabbit
Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: TBK1 Antibody detects endogenous levels of total TBK1/NAK protein.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy-terminus of TBK1/NAK. Antibodies were purified by protein A and peptide affinity chromatography.
抗体背景:

TBK1 (TANK-binding kinase 1)/NAK (NF-κB activating kinase) is an IκB kinase (IKK)-activating kinase and can activate IKK through direct phosphorylation (1). TBK1 was identified through association with the TRAF binding protein, TANK, and found to function upstream of NIK and IKK in the activation of NF-κB (2). TBK1/NAK induces IκB degradation and NF-κB activity through IKKβ. NAK may mediate IKK and NF-κB activation in response to growth factors that stimulate PKCε activity (1). TBK1 plays a pivotal role in the activation of IRF3 in the innate immune response (3).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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