2986 CNPase Antibody #2986

"上海博耀生物销售CNPase Antibody #2986，CST原装品质，价格优惠，订购CNPase Antibody #2986，详情请咨询销售人员！产品详细参

"上海博耀生物销售CNPase Antibody #2986，CST原装品质，价格优惠，订购CNPase Antibody #2986，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：CNPase Antibody #2986
货号：2986
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2986S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R	Endogenous	47	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： CNPase Antibody detects endogenous levels of total CNPase protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human CNPase. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

CNPase (2', 3’-cyclic nucleotide 3'-phosphodiesterase) catalyzes the in vitro hydrolysis of 2’, 3’-cyclic nucleotides to produce 2’-nucleotides. The in vivo molecular function and native substrate of this nucleotide phosphodiesterase remains under investigation (1). High CNPase expression is seen in oligodendrocytes and Schwann cells as CNPase accounts for roughly 4% of the total myelin protein in the central nervous system (2). CNPase binds to tubulin heterodimers and plays a role in tubulin polymerization, and oligodendrocyte process outgrowth (3). Typical myelination is seen in CNPase knock-out mice, but they suffer severe neurodegeneration from axonal loss and oligodendrocytes display abnormal paranodal loop structure prior to axonal degeneration. Paranodal loops typically contact the axolemma in axon-glial signaling; neurodegeneration in CNPase knock-out mice is a secondary consequence of impaired cell-cell communication (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-CD105/EndoglinCD105抗体
Anti-MID2/RNF60/Midline-2环指蛋白60抗体
Anti-ERα/ESR1雌激素受体α抗体
Anti-VEGFB血管内皮生长因子B
Anti-GJC2/Connexin 47间隙连接蛋白47抗体
ab102622/Anti-C10orf30 antibody
Anti-CD54/ICAM-1细胞间粘附分子-1抗体
Anti-OPN/BSP骨桥蛋白抗体(分泌型磷蛋白1)
ab101830/Anti-CST11 antibody
ab103584/Anti-FGL2 antibody
ab101189/Anti-alpha A Crystallin antibody
Anti-Cyclin B1周期素B1抗体
ab103046/Anti-GGCT antibody
ab101560/Anti-ACBD7 antibody
ab103399/Anti-FARS2 antibody
Anti-CDK7周期素依赖性激酶7抗体"
本页产品地址：http://www.geilan.com/sell/show-3244755.html