2940 p58IPK (C56E7) Rabbit mAb #2940

"上海博耀生物销售p58IPK (C56E7) Rabbit mAb #2940，CST原装品质，价格优惠，订购p58IPK (C56E7) Rabbit mAb #2940，详情请咨询

"上海博耀生物销售p58IPK (C56E7) Rabbit mAb #2940，CST原装品质，价格优惠，订购p58IPK (C56E7) Rabbit mAb #2940，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：p58IPK (C56E7) Rabbit mAb #2940
货号：2940
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2940S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP	H M Mk	Endogenous	58	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： p58IPK (C56E7) Rabbit mAb detects endogenous levels of total p58IPK protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human p58IPK.
抗体背景：

p58IPK is an inhibitor of interferon-induced and double-stranded RNA-activated protein kinase (PKR). It physically interacts with PKR and inhibits its activation and activity (1). Influenza virus activates p58IPK and thus blocks the activity of PKR to repress translation in the infected cells. In the uninfected cells, p58IPK forms a complex with its own inhibitor, HSP40, and is kept in an inactive state (2). ER stress induces the expression of p58IPK mediated by ATF6 (3,4). The induced p58IPK negatively regulates Perk activity, inhibits eIF2α phosphorylation and suppresses the activation of expression of downstream ER-responsive genes ATF4 and GADD153 (4). More recently, p58IPK has been shown to associate with the lumen of the endoplasmic reticulum (ER) where it is believed to serve as a cochaperone for BiP (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab100872/Anti-ABP1 antibody
ab103997/Anti-FAM54B antibody
ab103965/Anti-DDHD2 antibody
ab103891/Anti-DHFRL1 antibody
ab103108/Anti-GALNTL5 antibody
Anti-phospho-Tau protein(Thr498)磷酸化微管相关蛋白抗体
Anti-TBX2/T-box2抑癌基因抗体
Anti-TRH促甲状腺素释放激素抗体
ab102038/Anti-EDR1 / PHC1 antibody
Anti-CD5CD5抗体
ab103824/Anti-EFHC1 antibody
Anti-MCSF/M-CSF巨噬细胞克隆刺激因子抗体
ab10403/Anti-CXCR4 antibody
Anti-MICA/MHC IMHC I类链相关蛋白A/组织相容性复合物1抗体
ab103965/Anti-DDHD2 antibody
Anti-PCDHA8原钙粘附蛋白α8抗体"
本页产品地址：http://www.geilan.com/sell/show-3244716.html