2916 CDK7 (MO1) Mouse mAb #2916

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"上海博耀生物销售CDK7 (MO1) Mouse mAb #2916，CST原装品质，价格优惠，订购CDK7 (MO1) Mouse mAb #2916，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：CDK7 (MO1) Mouse mAb #2916
货号：2916
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2916P	40 ul (8 western blots)	询价
2916S	100 ul (20 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P IC-ABC	H R	Endogenous	40	Mouse IgG2b

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IC-ABC=Immunocytochemistry (ABC)
Reactivity Key:  H=Human  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： CDK7 (MO1) Mouse mAb detects endogenous levels of total CDK7 protein. The antibody does not cross-react with other CDKs.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with recombinant human CDK7.
抗体背景：

CDK-activating kinase (CAK) is a complex of CDK7 and cyclin H. The complex is involved in cell cycle regulation by phosphorylating an activating residue in the T-loop domain of cdks (1). Regulation of CAK activity is mediated by T-loop phosphorylation and by association with MAT1, both of which enhance its kinase activity toward the CTD of RNA polymerase II (2,3) and other substrates such as p53 (4). CAK is an essential component of the transcription complex TFIIH and may interact directly with TFIIH helicases (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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