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2897 Argonaute 2 (C34C6) Rabbit mAb #2897

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2897

更新时间:2013-07-28

浏览次数:712

公司地址:

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"上海博耀生物销售Argonaute 2 (C34C6) Rabbit mAb #2897,CST原装品质,价格优惠,订购Argonaute 2 (C34C6) Rabbit mAb #2897,

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"上海博耀生物销售Argonaute 2 (C34C6) Rabbit mAb #2897,CST原装品质,价格优惠,订购Argonaute 2 (C34C6) Rabbit mAb #2897,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Argonaute 2 (C34C6) Rabbit mAb #2897
货号:2897
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Monoclonal
规格:
No. Size Price
2897P 40 ul (4 western blots) 询价
2897S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Isotype
W IP H M R Endogenous 97 Rabbit IgG
Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Argonaute 2 (C34C6) Rabbit mAb detects endogenous levels of total Argonaute 2 protein.
来源及纯化方法: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to mouse Argonaute 2.
抗体背景:

Small non-coding RNAs are important regulators of gene expression in higher eukaryotes (1,2). Several classes of small RNAs, including short interfering RNAs (siRNAs) (3), microRNAs (miRNAs) (4), and Piwi-interacting RNAs (piRNAs) (5), have been identified. MicroRNAs are about 21 nucleotides in length and have been implicated in many cellular processes such as development, differentiation, and stress response (1,2). MicroRNAs regulate gene expression by modulating mRNA translation or stability (2). MicroRNAs function together with the protein components in the complexes called micro-ribonucleoproteins (miRNPs) (2). Among the most important components in these complexes are Argonaute proteins (1,2). There are four members in the mammalian Argonaute family and only Argonaute 2 (Ago2) possesses the Slicer endonuclease activity (1,2). Argonaute proteins participate in the various steps of microRNA-mediated gene silencing, such as repression of translation and mRNA turnover (1).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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