2891 Calreticulin Antibody #2891

"上海博耀生物销售Calreticulin Antibody #2891，CST原装品质，价格优惠，订购Calreticulin Antibody #2891，详情请咨询销售人员

"上海博耀生物销售Calreticulin Antibody #2891，CST原装品质，价格优惠，订购Calreticulin Antibody #2891，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Calreticulin Antibody #2891
货号：2891
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2891S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Mk	Endogenous	55	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Calreticulin Antibody detects endogenous levels of total calreticulin protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide surrounding Gln65 of human calreticulin. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Calcium is a universal signaling molecule involved in many cellular functions such as cell motility, metabolism, protein modification, protein folding, and apoptosis. Calcium is stored in the endoplasmic reticulum (ER), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP₃ Receptor channel (1). Calreticulin also functions as an ER chaperone that ensures proper folding and quality control of newly synthesized glycoproteins. As such, calreticulin presumably does not alter protein folding but regulates proper timing for efficient folding and subunit assembly. Furthermore, calreticulin retains proteins in non-native conformation within the ER and targets them for degradation (2,3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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