2890 Oct-4A (C52G3) Rabbit mAb #2890

"上海博耀生物销售Oct-4A (C52G3) Rabbit mAb #2890，CST原装品质，价格优惠，订购Oct-4A (C52G3) Rabbit mAb #2890，详情请咨询

"上海博耀生物销售Oct-4A (C52G3) Rabbit mAb #2890，CST原装品质，价格优惠，订购Oct-4A (C52G3) Rabbit mAb #2890，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Oct-4A (C52G3) Rabbit mAb #2890
货号：2890
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2890S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IHC-P IF-IC F ChIP	H	Endogenous	45	Rabbit IgG

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry  ChIP=Chromatin IP
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Oct-4A (C52G3) Rabbit mAb detects endogenous levels of total Oct-4A protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human Oct-4A.
抗体背景：

Oct-4 (POU5F1) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells (1). A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation (2,3). Research studies have demonstrated that Oct-4 is a useful germ cell tumor marker (4). Oct-4 exists as two splice variants, Oct-4A and Oct-4B (5). Recent studies have suggested that the Oct-4A isoform has the ability to confer and sustain pluripotency, while Oct-4B may exist in some somatic, non-pluripotent cells (6,7).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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