2887 ERp57 (A484) Antibody #2887

"上海博耀生物销售ERp57 (A484) Antibody #2887，CST原装品质，价格优惠，订购ERp57 (A484) Antibody #2887，详情请咨询销售人员

"上海博耀生物销售ERp57 (A484) Antibody #2887，CST原装品质，价格优惠，订购ERp57 (A484) Antibody #2887，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：ERp57 (A484) Antibody #2887
货号：2887
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2887S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R	Endogenous	57	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： ERp57 (A484) Antibody detects endogenous levels of total ERp57 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala484 of human ERp57. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Secretory proteins translocate into the endoplasmic reticulum (ER) after their synthesis where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds (1). This process is called oxidative protein folding. Disulfide isomerase (PDI) has two thioredoxin homology domains and catalyzes the formation and isomerization of these disulfide bonds (2). Other ER resident proteins that possess the thioredoxin homology domains, including endoplasmic reticulum stress protein 57 (ERp57), constitute the PDI family (2). ERp57 interacts with calnexin and calreticulin (3) and is suggested to play a role in the isomerization of disulfide bonds on certain glycoproteins (3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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