产品简介
"上海博耀生物销售ERp44 Antibody #2886,CST原装品质,价格优惠,订购ERp44 Antibody #2886,详情请咨询销售人员!产品详细参数
产品说明
"上海博耀生物销售
ERp44 Antibody #2886,CST原装品质,价格优惠,订购
ERp44 Antibody #2886,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:ERp44 Antibody #2886
货号:2886
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 2886S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
H M R Mk |
Endogenous |
44 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Mk=Mon
key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
ERp44 Antibody detects endogenous levels of total ERp44 protein.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human ERp44. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:
Secretory proteins translocate into the endoplasmic reticulum (ER) after their synthesis where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds (1). This process is called oxidative protein folding. Disulfide isomerase (PDI) has two thioredoxin homology domains and catalyzes the formation and isomerization of these disulfide bonds (2). Other ER resident proteins that possess the thioredoxin homology domains, including endoplasmic reticulum resident protein 44 (ERp44), constitute the PDI family (2). ERp44 is induced upon ER stress and is linked to Ero1-Lα and Ero1-Lβ through mixed disulfide bonds (3). ERp44 was shown to mediate the ER localization of Ero1-Lα (4).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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