产品简介
"上海博耀生物销售CASK Antibody #2878,CST原装品质,价格优惠,订购CASK Antibody #2878,详情请咨询销售人员!产品详细参数如
产品说明
"上海博耀生物销售
CASK Antibody #2878,CST原装品质,价格优惠,订购
CASK Antibody #2878,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:CASK Antibody #2878
货号:2878
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 2878S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
H M R |
Endogenous |
105 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
CASK Antibody detects endogenous levels of total CASK protein.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the amino-terminus of CASK. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:
CASK is an adaptor protein with a calcium/calmodulin-dependent protein kinase domain, an SH3 domain, a guanylate kinase homology domain (GUK), and a PDZ domain. CASK links transmembrane proteins to the cytoskeleton and signaling molecules. In particular, CASK binds to neurexin to stabilize pre- and post-synaptic structures (1). While most CASK protein (~80%) is cytoplasmic, a portion of the protein enters the nucleus, where it acts as a transcriptional coactivator (2). Transgenic mice with CASK insertional mutations die within 24 hours of birth (3).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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