2858 eIF4GI Antibody #2858

"上海博耀生物销售eIF4GI Antibody #2858，CST原装品质，价格优惠，订购eIF4GI Antibody #2858，详情请咨询销售人员！产品详细参

"上海博耀生物销售eIF4GI Antibody #2858，CST原装品质，价格优惠，订购eIF4GI Antibody #2858，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：eIF4GI Antibody #2858
货号：2858
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2858S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IHC-P IF-IC	H M R	Endogenous	220	Rabbit

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： eIF4GI Antibody detects endogenous levels of total eIF4GI protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human eIF4GI. Antibodies are purified by peptide affinity chromatography.
抗体背景：

The initiation of translation is an important biological event and a variety of factors contribute to this process. Members of the eIF4 translation initiation factor family bind to the 5' m⁷GTP mRNA cap and unwind the mRNA secondary structure (1,2). The amino-terminal portion of eIF4G physically associates with eIF4E to stimulate the binding of eIF4E to the mRNA cap structure (3). eIF4G also interacts with eIF3 and eIF4A and serves as an adaptor molecule in the eIF4 complex (4). Moreover, eIF4G plays a role in internal ribosomal entry site (IRES)-mediated initiation of translation (5,6). The eIF4G family includes eIF4G1 (eIF4GI), eIF4G2 (p97, DAP5 or NAT1), and eIF4G3 (eIF4GII) (7). These factors share a homologous sequence that provides for interaction with initiation factors eIF3 and eIF4A. Both eIF4G1 and eIF4G3 are involved in cap-dependent translation, while eIF4G2 plays a role in IRES-mediated translation of some genes during cell stress (7,8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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