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2816 Grp75 Antibody #2816

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2816

更新时间:2013-07-28

浏览次数:672

公司地址:

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产品简介

"上海博耀生物销售Grp75 Antibody #2816,CST原装品质,价格优惠,订购Grp75 Antibody #2816,详情请咨询销售人员!产品详细参数

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"上海博耀生物销售Grp75 Antibody #2816,CST原装品质,价格优惠,订购Grp75 Antibody #2816,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Grp75 Antibody #2816
货号:2816
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
2816S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W IF-IC H M R Mk Endogenous 75 Rabbit
Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Grp75 Antibody detects endogenous levels of total Grp75 protein.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to a sequence of human Grp75. Antibodies are purified by peptide affinity chromatography.
抗体背景:

Grp75, also known as mortalin, is a member of Hsp70 family of chaperone proteins that is not heat-inducible (1,2). This protein is essential for transporting many mitochondrial proteins from the cytoplasm to mitochondria (3). Grp75 inactivates the tumor suppressor p53 (4). Studies found that Grp75 is overexpressed in many tumor tissues and immortalized human cell lines, suggesting its role in the tumor formation (5). Grp75 is also implicated in cell aging, as its overexpression appears to prolong the life span of human fibroblasts (6).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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