2810 Survivin (71G4B7) Rabbit mAb (Alexa Fluor 488 Conjugate) #2810

Survivin (71G4B7) Rabbit mAb (Alexa Fluor 488 Conjugate) #2810，CST原装品质，价格优惠，订购Survivin (71G4B7) Rabbit mAb (Alexa Fluor 488 Conjugate) #2810，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Survivin (71G4B7) Rabbit mAb (Alexa Fluor 488 Conjugate) #2810
货号：2810
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2810S	100 ul (50 tests)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
IF-IC F	H M R	Endogenous	16	Rabbit IgG

Applications Key:  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Survivin (71G4) Rabbit mAb detects endogenous levels of total survivin protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Cys60 of human survivin. The antibody was conjugated to Alexa Fluor^® 488 under optimal conditions with an F/P ratio of 2-5.
抗体背景：

Survivin is a 16 kDa anti-apoptotic protein highly expressed during fetal development and cancer cell malignancy (1). Survivin binds and inhibits caspase-3, controlling the checkpoint in the G2/M-phase of the cell cycle by inhibiting apoptosis and promoting cell division (2,3). This regulatory process requires the phosphorylation of survivin at Thr34 by p34 cdc2 kinase (4). Gene targeting using a Thr34 phosphorylation-defective survivin mutant, as well as antisense survivin, have been shown to inhibit tumor growth (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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