2808 Survivin (71G4B7) Rabbit mAb #2808

"上海博耀生物销售Survivin (71G4B7) Rabbit mAb #2808，CST原装品质，价格优惠，订购Survivin (71G4B7) Rabbit mAb #2808，详情

"上海博耀生物销售Survivin (71G4B7) Rabbit mAb #2808，CST原装品质，价格优惠，订购Survivin (71G4B7) Rabbit mAb #2808，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Survivin (71G4B7) Rabbit mAb #2808
货号：2808
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2808P	40 ul (4 western blots)	询价
2808S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P IHC-F IF-IC F	H M R	Endogenous	16	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IHC-F=Immunohistochemistry (Frozen)  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Survivin (71G4B7E) Rabbit mAb detects endogenous levels of total Survivin protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding cysteine 60 of human Survivin.
抗体背景：

Survivin is a 16 kDa anti-apoptotic protein highly expressed during fetal development and cancer cell malignancy (1). Survivin binds and inhibits caspase-3, controlling the checkpoint in the G2/M-phase of the cell cycle by inhibiting apoptosis and promoting cell division (2,3). This regulatory process requires the phosphorylation of survivin at Thr34 by p34 cdc2 kinase (4). Gene targeting using a Thr34 phosphorylation-defective survivin mutant, as well as antisense survivin, have been shown to inhibit tumor growth (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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