2802 Survivin (6E4) Mouse mAb #2802

"上海博耀生物销售Survivin (6E4) Mouse mAb #2802，CST原装品质，价格优惠，订购Survivin (6E4) Mouse mAb #2802，详情请咨询销

"上海博耀生物销售Survivin (6E4) Mouse mAb #2802，CST原装品质，价格优惠，订购Survivin (6E4) Mouse mAb #2802，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Survivin (6E4) Mouse mAb #2802
货号：2802
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2802S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H Mk	Endogenous	16	Mouse IgG1

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Survivin (6E4) Mouse mAb detects endogenous levels of human survivin. The antibody does not cross-react with other types of apoptotic inhibitor proteins.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino-terminal sequence of human survivin.
抗体背景：

Survivin is a 16 kDa anti-apoptotic protein highly expressed during fetal development and cancer cell malignancy (1). Survivin binds and inhibits caspase-3, controlling the checkpoint in the G2/M-phase of the cell cycle by inhibiting apoptosis and promoting cell division (2,3). This regulatory process requires the phosphorylation of survivin at Thr34 by p34 cdc2 kinase (4). Gene targeting using a Thr34 phosphorylation-defective survivin mutant, as well as antisense survivin, have been shown to inhibit tumor growth (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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