产品简介
"上海博耀生物销售Phospho-PEA-15 (Ser104) Antibody #2776,CST原装品质,价格优惠,订购Phospho-PEA-15 (Ser104) Antibody #27
产品说明
"上海博耀生物销售
Phospho-PEA-15 (Ser104) Antibody #2776,CST原装品质,价格优惠,订购
Phospho-PEA-15 (Ser104) Antibody #2776,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:Phospho-PEA-15 (Ser104) Antibody #2776
货号:2776
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 2776S |
100 ul (10 western blots) |
询价 |
| 2776L |
300 ul (30 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W IP |
H R (M) |
Endogenous |
15 |
Rabbit |
Applications Key:
W=Western Blotting
IP=Immunoprecipitation
Reactivity Key:
H=Human
M=Mouse
R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
Phospho-PEA-15 (Ser104) Antibody detects endogenous levels of PEA-15 only when phosphorylated at serine 104.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser104 of human PEA-15. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:
PEA-15 is a 15 kDa phosphoprotein expressed abundantly in astrocytes and fibroblasts as well as in tissues, including the lung and eye (1). The protein has been shown to coordinate cell growth, death, and glucose ultilization (2-4). The amino-terminal DED domain of PEA-15 mediates its binding to FADD or Erk and futher regulates the Erk and apoptosis signaling pathways. PEA-15 can be phosphorylated at two serine residues, Ser104 and Ser116, located within the carboxy terminus. Phosphorylation at these sites regulates binding to Erk and FADD (2,3).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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