2765 Ribosomal Protein L13a Antibody #2765

"上海博耀生物销售Ribosomal Protein L13a Antibody #2765，CST原装品质，价格优惠，订购Ribosomal Protein L13a Antibody #2765

"上海博耀生物销售Ribosomal Protein L13a Antibody #2765，CST原装品质，价格优惠，订购Ribosomal Protein L13a Antibody #2765，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Ribosomal Protein L13a Antibody #2765
货号：2765
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2765S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H Mk	Endogenous	23	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Ribosomal Protein L13a Antibody detects endogenous levels of total ribosomal protein L13a.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human ribosomal protein L13a. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Ribosomal protein L13a (RPL13a, 60S ribosomal protein L13a) is a member of the L13 ribosomal protein family and a structural component of the 60S ribosomal subunit (1). RPL13a appears to play an important role in transcript-specific translational silencing. Interferon-γ induces the phosphorylation of RPL13a and triggers the release of this protein from the 60S ribosomal subunit (2). Free RPL13a protein binds to the GAIT (interferon-γ-activated inhibitor of translation) complex at the 3'-UTR of ceruloplasmin (Cp) mRNA to repress Cp expression (2). RPL13a bound to the GAIT complex interacts with eIF4G, which prevents the recruitment of 43S ribosomal subunit and results in transcript-specific translation suppression (3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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