2748 Sox2 Antibody #2748

"上海博耀生物销售Sox2 Antibody #2748，CST原装品质，价格优惠，订购Sox2 Antibody #2748，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售Sox2 Antibody #2748，CST原装品质，价格优惠，订购Sox2 Antibody #2748，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Sox2 Antibody #2748
货号：2748
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2748S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP ChIP	H M (R) (Mk) (B) (Dg) (Hr)	Endogenous	35	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  ChIP=Chromatin IP
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  B=Bovine  Dg=Dog  Hr=Horse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Sox2 Antibody detects endogenous levels of total Sox2 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino acids surrounding Gly179 of human Sox2. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Embryonic stem cells are derived from the inner cell mass of the blastocyst and are unique in their pluripotent capacity and potential for self-renewal. Sox2 is one of a set of transcription factors that are crucial for the maintenance of pluripotency (1). Sox2, Oct-4, and Nanog cooperate in this network (1-3), and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency (4,5). Chromatin immunoprecipitation experiments have shown that Sox2 and Oct-4 bind to thousands of gene regulatory sites, highlighting the importance of these transcription factors in early embryonic development (6,7). It has recently been shown that Sox2 is amplified in lung and esophageal squamous cell tumors (8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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