2746 FEN-1 Antibody #2746

"上海博耀生物销售FEN-1 Antibody #2746，CST原装品质，价格优惠，订购FEN-1 Antibody #2746，详情请咨询销售人员！产品详细参数

"上海博耀生物销售FEN-1 Antibody #2746，CST原装品质，价格优惠，订购FEN-1 Antibody #2746，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：FEN-1 Antibody #2746
货号：2746
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2746S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Mk	Endogenous	45	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： FEN-1 Antibody detects endogenous levels of total FEN-1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino acids surrounding Lys313 of human FEN-1. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Flap endonuclease-1 (FEN-1) is a structure-specific nuclease with multiple functions in DNA processing pathways (1,2). The replication and DNA repair activities of FEN-1 are critical for genomic stability in the eukaryotic cell. Through interaction with proliferation cell nuclear antigen (PCNA), FEN-1 helps coordinate Okazaki fragment maturation by removing RNA-DNA primers (3). FEN-1 is also required for non-homologous end joining of double stranded DNA breaks in long patch base excision repair (4,5). The multi-functional activities of FEN-1 are regulated by various mechanisms, including protein partner interactions (6,7), post-translational modifications (8,9), and subcellular re-localization in response to cell cycle or DNA damage (10).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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