2744 SPINK3 Antibody #2744

"上海博耀生物销售SPINK3 Antibody #2744，CST原装品质，价格优惠，订购SPINK3 Antibody #2744，详情请咨询销售人员！产品详细参

"上海博耀生物销售SPINK3 Antibody #2744，CST原装品质，价格优惠，订购SPINK3 Antibody #2744，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：SPINK3 Antibody #2744
货号：2744
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2744S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	M R	Endogenous	10	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： SPINK3 Antibody detects endogenous levels of total SPINK3 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the carboxy terminus of the mouse SPINK3 protein. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The Kazal type 3 serine peptidase inhibitor (SPINK3) is a serine peptidase inhibitor expressed in the adult pancreas that protects acinar cells from trypsin-induced cell damage (1). Ingestion of milk by newborn SPINK3 knock out mice triggers autophagic cell death in pancreatic acinar cells and the complete disappearance of the pancreas (2). Mutations in the human SPINK3 homolog (known as SPINK1) are associated with chronic pancreatitis, presumably through decreased protection against trypsin-induced autophagic cell death (1,3). SPINK3 may be involved in the embryonic development of several other tissues (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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